23 and Me Health Report
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Good news if you have done 23 and Me and opted for the health report you can find out if it is genetically possible for you to be a carrier of the Celiac gene and also if you have a chance of developing it.
Most Celiac patients have the HLA DQ2.5 which is confirmed by SNP rs2187668, though this gene is fairly common among Europeans so again having this does not mean that you have Celiac but it is possible you could develop it in your lifetime; please seek medical advice.
Here is how you unlock your data and find out if you could possible get Celiac Disease:
Step One: Log into your 23 and me account (You must be signed in for the link to work).
Step Two: Go to Tools.
Step Three: Click on raw data and activate it.
Now lets check your genes:
You Must Be Signed Into 23 and me.
Check your 23andMe link rs2187668: (most Celiacs have this Gene in combination with the gene below)
CC no risk for Celiac unless HLA DQ8 check below
CT one allele for HLA DQ2.5 Celiac disease is possible
TT two alleles for HLA DQ2.5 Celiac disease is possible
Check your 23andMe Link rs7454108:
CC two alleles for HLA DQ8 (Celiac disease is possible)
CT one allele for HLA DQ8 (Celiac disease is possible)
TT wildtype
Increased risk of celiac disease.
Check your 23andMe results for rs601338:
AA increased risk of celiac
AG no increased risk
GG no increased risk
Add On Notes If You Have Siblings:
They have found genes that will tell you if your siblings have a higher risk of also developing the disease.
Link for 23 and me results for rs1464510:
AA increased risk of celiac
AC increased risk of celiac
CC no increased risk
Link for 23 and me 23andMe results for rs842647:
AA increased risk of celiac
AG increased risk of celiac
GG no increased risk
Link for 23andMe results for rs2816316:
AA increased risk of celiac
AC increased risk of celiac
CC no increased risk